We played this with 6 (four players, two swamp ghosts) and it was a complete blast. It went into some pretty dark places and the characters paid in full for their crimes against humanity (and themselves) so I would absolutely not recommend this for anyone under 12 or so. The game is not balanced--- if you know the cards you will be able to figure out pretty quick who is going to 'win,' except for the Swamp Ghost factor-- who are the great equalizer in the game in that they can make sure certain player's characters die during each act. Players who end up as swamp ghosts hold grudges and make those players lose, usually in spectacular fashion. What it adds up to is a frantic and extremely engaging mutual story telling experience. If nothing else, a 3 hour session of this will make your players better at all other RPG's in terms of character development and discourse. I cannot wait for more sets of cards along these lines.
[5 of 5 Stars!]